Florence is a small city with an enormous place in history. Nestled among the Tuscan hills, Firenze was the birthplace of the Renaissance, home of the powerful Medici family and the place where artists like Michelangelo and Brunelleschi created some of the world's greatest masterpieces. Walking its streets, past medieval palaces and church facades, it's easy to imagine yourself centuries in the past, until you pass the stylish boutiques of Via de' Tornabuoni.

Stand before Michelangelo's David at the Accademia, marvel at Brunelleschi's soaring dome on the Duomo, and spend hours among the masterpieces of the Uffizi Gallery. Cross the shop-lined Ponte Vecchio, wander the Boboli Gardens and climb to Piazzale Michelangelo for a sunset view over the rooftops. But art isn't the only reason to come. Florence is also about long Tuscan meals, great wine, leather markets and a romantic atmosphere around every corner.

Florence's top museums sell out, so booking ahead is a must. I'll reserve your tickets and guides, choose a hotel in the historic center and add day trips to Tuscany's hill towns and wineries.