Alexander von Humboldt is often credited with calling Lake Atitlan the most beautiful lake in the world, and many travelers agree. High in the Guatemalan Highlands, this deep blue lake fills an ancient volcanic caldera and is ringed by three towering volcanoes and a dozen traditional Mayan villages, each with its own character.

Travel between villages by boat. Panajachel is the lively main town, with busy markets and lakefront restaurants. San Marcos is a peaceful retreat known for yoga and wellness, and San Juan La Laguna is home to colorful murals and women's weaving cooperatives where you can see traditional textiles being made. Kayak on the lake at sunset, hike for views from above, and climb Volcan San Pedro for a challenging adventure. Visit the market in nearby Chichicastenango for an unforgettable cultural experience.

To get there, fly into Guatemala City and take a scenic drive of about three hours through the mountains. The first glimpse of the lake shimmering far below is breathtaking. I'll plan your transfers, a lakeside hotel and a trusted guide, and pair Atitlan with Antigua and Tikal.